7. Gastroesophageal Reflux Disease (GERD)

GERD is a condition that often leads to acid reflux, also known as heart burn. GERD can also lead to dysphagia or difficulty swallowing, resulting in excess salivation and drooling while sleeping. This is another important condition that does have a solution, so speak to your doctor if you have frequent heartburn and are drooling while sleeping.
8. Neurological Conditions

Conditions such as stroke, Parkinson’s disease, Alzheimer’s, Huntington’s disease, Bell’s Palsy, Cerebral Palsy, ALS, and brain damage can lead to sialorrhea, making it harder to swallow and causing drooling during sleep. Interestingly enough, a vitamin B12 deficiency can also lead to drooling issues. This is because a deficiency in B12 can also lead to neurological problems, hence the drooling.
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